Triptan therapy in migraine.
نویسنده
چکیده
n engl j med 363;1 nejm.org july 1, 2010 63 This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major clinical studies, the clinical use of this therapy, and potential adverse effects are reviewed. Relevant formal guidelines, if they exist, are presented. The article ends with the author’s clinical recommendations. Triptan Therapy in Migraine
منابع مشابه
Costs and utilization of triptan users who receive drug prophylaxis for migraine versus triptan users who do not receive drug prophylaxis.
OBJECTIVES The objectives were 2-fold: (1) to describe the utilization patterns of new users of triptan therapy and (2) to measure the direct (pharmacy and medical) costs of migraine-related health care services in moderate-to-severe migraine patients treated with drug prophylaxis compared with migraine patients who are not treated with drug prophylaxis. METHODS A retrospective administrative...
متن کاملHealth care resource utilization following initiation of a triptan: a retrospective claims analysis.
BACKGROUND 23 million Americans suffer from migraine headaches, incurring more than $1 billion in direct medical costs each year (with another $13 billion in indirect productivity losses). Triptans are the most common treatment of choice for these patients; however, adherence and persistence to triptans are poor. Partly due to poor adherence to therapy, the ability of triptans to reduce the uti...
متن کاملTriptan use as a function of cardiovascular risk. A population-based study.
AIM To estimate the proportion of individuals with migraine using triptan therapy as a function of their cardiovascular (CV) profile and disease severity. METHODS As a part of the American Migraine Prevalence and Prevention study, we identified migraineurs representative of the U.S. adult population. Triptan use was estimated as a function of presence of CV disease (CVD), of CV risk factors, ...
متن کاملAlmotriptan efficacy in migraine with allodynia: a critique of Schoenen et al.
In a randomized, double-blind, cross-over, multicentre study, Schoenen and his colleagues (Cephalalgia 2008; 28:1095–105) examined whether the efficacy of triptan migraine therapy (alone, or in combination with non-steroidal anti-inflammatory drugs) was influenced by the presence of cutaneous allodynia at the time of treatment. In contrast with our earlier work (1), the authors concluded that t...
متن کاملPreventive Therapies for Migraine Headache
In most cases, patients do not experience complete resolution of their headaches; rather, the headaches become less frequent and less severe. As a result, the usual measure of success in prevention is a reduction of headache occurrence by 50% or more. Reducing headache frequency and severity can significantly improve quality of life and lessen the use of acute pharmacological treatment. Prevent...
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عنوان ژورنال:
- The New England journal of medicine
دوره 363 1 شماره
صفحات -
تاریخ انتشار 2010